Osteopontin
نویسندگان
چکیده
منابع مشابه
The association between osteopontin gene polymorphisms, osteopontin expression and sarcoidosis
BACKGROUND Sarcoidosis is a systemic inflammatory disease of unknown etiology. Osteopontin (SPP1, OPN) is an extra cellular matrix glycoprotein and cytokine with a known role in granuloma formation and in autoimmune and inflammatory diseases. OBJECTIVE To determine whether plasma OPN levels are elevated in patients with sarcoidosis and compare the frequency of four single nucleotide polymorph...
متن کاملMesothelin and osteopontin.
The review by PANTAZOPOULOS et al. [1] on mesothelin and osteopontin was timely and well written. However, I would like to comment on some of the statements that were made. Firstly, it states that ‘‘patients with early-stage disease can survive for more than 5 years if the tumour is promptly resected’’. This implies that resection would benefit the patient, which is far from proven; there is no...
متن کاملOsteopontin and oral carcinogenesis
down-regulation of osteopontin and breast tumour progression in vivo is highly interesting [1]. Recent studies indicate a close association between not only breast cancer and osteopontin but other systemic malignancies as well. Studies over the past few years have especially shown a strong relationship between osteopontin expression and oral carcinogenesis. For instance, Devoll et al. in a rece...
متن کاملMesothelin and osteopontin
The review by PANTAZOPOULOS et al. [1] on mesothelin and osteopontin was timely and well written. However, I would like to comment on some of the statements that were made. Firstly, it states that ‘‘patients with early-stage disease can survive for more than 5 years if the tumour is promptly resected’’. This implies that resection would benefit the patient, which is far from proven; there is no...
متن کاملNeuroprotection by osteopontin in stroke.
Osteopontin (OPN) is a secreted extracellular phosphoprotein involved in diverse biologic functions, including inflammation, cell migration, and antiapoptotic processes. Here we investigate the neuroprotective potential of OPN to reduce cell death using both in vitro and in vivo models of ischemia. We show that incubation of cortical neuron cultures with OPN protects against cell death from oxy...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2007
ISSN: 1079-5642,1524-4636
DOI: 10.1161/atvbaha.107.144824